Open Access
Research Article

Table 1.

Sarcoptes scabiei var. canis mite counts of naturally infested dogs administered either NexGard® or NexGard Spectra® per label instruction twice, one month apart (Visit 1 and Visit 2) and percentage efficacy of treatments.

Live Sarcoptes mite counts in five skin scrapings
Geometric mean2 (Range) Efficacy3 (%) p-value4
N+/NG1 Arithmetic mean (Standard deviation)
NexGard ®
 Visit 1, baseline (pre-treatment) 38/38 6.0 (5–18)
6.1 (2.67)
 Visit 2, one month after Visit 1 1/38 0.1 (0–10) 98.9 <0.0001
0.3 (1.62) 95.8
 Visit 3, one month after Visit 2 1/38 <0.1 (0–1) 99.7 <0.0001
<0.1 (0.16) 99.6
NexGard Spectra ®
 Visit 1, baseline (pre-treatment) 27/27 6.0 (5–11)
6.1 (1.30)
 Visit 2, one month after Visit 1 1/27 <0.1 (0–1) 99.6 <0.0001
<0.1 (0.19) 99.4
 Visit 3, one month after Visit 2 0/27 0 100 <0.0001
0 100
1

N+/NG: Number of dogs tested positive for live Sarcoptes mites/Number of dogs examined.

2

Geometric mean, based on transformation to the logarithm of (count + 1).

3

Efficacy (%) = 100 × [(Visit 1 geometric or arithmetic mean mite count − Visit 2 or Visit 3 geometric or arithmetic mean mite count)/Visit 1 geometric or arithmetic mean mite count].

4

Probability from within-group-analysis using Wilcoxon(-Pratt test) at α = 0.05.