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Table 3

P-type transport ATPases in genomes of eight species of Leishmania.

Protein Size (aa) Chromosome Accession Protein Size (aa) Chromosome Accession
P1B, Cu++, Co++ transport P3A, H+ transport
LM1 1163 33 Q4Q3X8 LM8 974 18 Q4QDN8
LT1 1163 33 LtrL590_330029000 LT8 absent
LI1 1163 33 A4I980 LI8 974 18 A4HY23
LD1 1163 33 E9BQF1 LD8 49 (p), 84 (p) 18 E9BDY0 + E9BDY1
LA1 1163 33 LAEL147_000688800 LA8 950 18 LAEL147_000273500
LMx1 1246 32 E9B447 LMx8 533 (p) 18 E9ART5LI4
LP1 1224 33 LpaL13_330029400 LP8 927 18 LpaL13_180018000
LB1 1136 33 A4HLS1 LB8 927 18 A4H9Q5
P2A, Ca++ transport (SERCA)
LM2 1023 4 Q95Z93 LM9 974 18 Q4QDN7
LT2 1023 4 LtrL590_040005000 LT9 764 (p) 18 LtrL590_180020500
LI2 1023 4 A4HRZ6 LI9 974 18 A4HY22
LD2 1023 4 E9B7W7 LD9 974 18 E9BDY2
LA2 1023 4 LAEL147_000046100 LA9 158 (p) 18 LAEL147_000273600
LMx2 1013 4 E9AJY3 LMx9 974 18 E9ART6
LP2 1025 4 LpaL13_040005600 LP9 Absent
LB2 1025 4 A4H3S2 LB9 463 (p), 338 (p) 18 A4H9S1, A4H9S2
P2B, Ca++ transport (PMCA) P4, aminophospholipid translocation
LM3 1104 7 Q4QIM8 LM11 1279 30 Q4Q767
LT3 872 (p) 7 LtrL590_070012400 LT11 1447 30 LtrL590_300028400
LI3 929 7 A4HTF0 LI11 1279 30 A4I5Q4
LD3 937 7 E9B963 LD11 1279 30 E9BLX0
LA3 875 7 LAEL147_000094200 LA11 1447 30 LAEL147_000570400
LMx3 1104 7 E9AL76 LMx11 1279 29 E9B0Z9
LP3 686 (p) 7 LpaL13_070012000 LP11 1369 30 LpaL13_300026500
LB3 1126 7 A4H514 LB11 1244 30 A4HIF8
LM4 1119 7 Q4QIM6 LM12 1491 34 Q4Q2T2
LT4 Absent LT12 1491 34 LtrL590_340031100
LI4 294 (p), 863 (p) 7 E9AG74, A4HT82 LI12 1491 34 A4IA39
LD4 328 (p) 7 E9B965 LD12 1491 34 E9BR44
LA4 293 (p), 275 (p) 7 LAEL147_000094300 LA12 1491 34 LAEL147_000729000
LMx4 1119 7 E9AL78 LMx12 1483 33 E9B554
LP4 181 (p), 592 (p) 7 LpaL13_070012300 LP12 1510 20 LpaL13_200028900
LB4 592 (p) 7 A4H516 LB12 1510 20 A4HAY0
LM5 1194 33 Q4Q490 LM13 1157 34 Q4Q2M2
LT5 1224 33 LtrL590_330016200 LT13 1158 34 LtrL590_340037100
LI5 1197 33 A4I8W5 LI13 1157 34 A4IA89
LD5 1197 33 E9BQ35 LD13 1157 34 E9BR98
LA5 1221 33 LAEL147_000675700 LA13 1158 34 LAEL147_000735700
LMx5 1198 32 E9B3T4 LMx13 1158 33 E9B5B1
LP5 1221 33 LpaL13_330015600 LP13 336 (p), 373 (p) 20 LpaL13_200034700
LB5 1194 33 A4HLF4 LB13 666 (p) 20 LbrM.20.2800
LM6 1051 17 Q4QED4 LM14 2525 9 Q4QHT5
LT6 1134 17 LtrL590_170010400 LT14 2510 9 LtrL590_090014400
LI6 1134 17 A4HXD4 LI14 2528 9 A4HU10
LD6 1134 17 E9BD87 LD14 2528 9 E9B9Y1
LA6 1134 17 LAEL147_000247600 LA14 2511 9 LAEL147_000122200
LMx6 1135 17 E9AR29 LMx14 2526 9 E9AMU0
LP6 1113 17 LpaL13_170011200 LP14 2441 NA LpaL13_000026300
LB6 1113 17 A4H903 LB14 2441 9 A4H5N8
LM15 1097 13 Q4QG01
P2D, Na+ transport
LM7 1109 35 E9AF31 LT15 1097 13 LtrL590_130020500
LT7 1224 35 LtrL590_350026000 LI15 1097 13 A4HVT2
LI7 1109 35 A4IBA6 LD15 1097 13 E9BBN1
LD7 1109 35 E9BS80 LA15 1097 13 LAEL147_000187900
LA7 1223 35 LAEL147_000770700 LMx15 1104 13 E9APH7
LMx7 1225 34 E9B686 LP15 1096 13 LpaL13_130018700
LP7 1216 34 LpaL13_340025100 LB15 1097 13 A4H7E2
LB7 1104 34 A4HMM8 LB17 1068 13 A4H7E4
P3A, H+ transport P5A, unknown ion specificity
LM10 952 4 O97198 LM16 1244 7 Q4QII2
LT10 957 4 LtrL590_040016000 LT16 1244 7 LtrL590_070018400
LI10 957 4 A4H5A9 LI16 1244 7 A4HTD0
LD10 957 4 E9B877 LD16 1244 7 E9B9A4
LA10 957 4 LAEL147_000057500 LA16 1244 7 LAEL147_000099500
LMx10 910 4 E9AK92 LMx16 1244 7 E9ALC3
LP10 544 (p), 327 (p) 4 LpaL13_0400179(8)00 LP16 1243 7 LpaL13_070016500
LB10 930 (PG) 4 LbrM.04.1120 LB16 1243 7 A4H553

Notes. LA, Leishmania aethiopica (strain L147); LB, L. braziliensis (strain MHOM/BR/75/M2904); LD, L. donovani (strain BPK282A1); LI, L. infantum (strain JPCM5); LM, L. major (strain Friedlin); LMx, L. mexicana (strain MHOM/GT/2001/U1103); LP, L. panamensis (strain MHOM/COL/81/L130; LT, L. tropica (strain L590); NA, not assigned; (p), partial open reading frame(s); PG, pseudogene (internal stop codons). Accession numbers are from the UniProtKB (http://www.uniprot.org) or from the TriTrypDB databases (http://tritrypdb.org).