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Review Article

Table 4

P-type transport ATPases in genomes of four species of Trypanosoma.

Protein Size (aa) Chromosome Accession Protein Size (aa) Chromosome Accession
P1B, Cu++, Co++ transport P3A, H+ transport
TB1 961 11 Q387C6 TB8 920 10 Q388Z2
TBL1 961 11 Tb427tmp.47.0023 TBL8 920 10 Tb427.10.12510
TBG1 961 11 D0A5R6 TBG8 Absent
TC1s/1p 954 39-S, 39-P Q4DIX9, Q4D866 TC8s 259 (p) 40-S Q4CRY5
TC8p 256 (p) 40-P Q4DL30
P2A, Ca++ transport (SERCA)
TB2 1011 5 Q57Z55 TB9 912 10 Q388Z3
TBL2 1011 5 Tb427.05.3400 TBL9 912 10 Tb427.10.12500
TBG2 1011 5 C9ZPL1 TBG9 912 10 D0A564
TC2s 1006 21-S Q4DIM7 TC9s 219 (p) 40-S Q4CP01
TC9p 484 (p) 40-P Q4CNY1
P2B, Ca++ transport (PMCA)
TB3 1080 8 D6XMU9 TB10 Absent
TBL3 1080 8 Tb427.08.1200 TBL10 Absent
TBG3 1077 8 C9ZUN6 TBG10 Absent
TC3s/3p 1101, 1103 19-S, 19-P Q4E3S6, Q4DSJ2 TC10s 898 8-S Q4DE37
TB4 1106 8 Q57VN6 P4, aminophospholipid translocation
TBL4 1106 8 Tb427.08.1180 TB11 1196 6 Q584Z5
TBG4 Absent TBL11 1196 6 Tb427.06.3550
TC4 Absent TBG11 1196 6 C9ZR23
TC11s/11p 1217 32-S, 32-P Q4DXI9, Q4DT76
TB4b 1102 8 Q57VN8
TBL4b 1102 8 Tb427.08.1160 TB12 Absent
TBG4b Absent TBL12 Absent
TC4b Absent TBG12 Absent
TC12s 1259 34-S Q4DPV1
TB5 1100 10 Q389H9
TBL5 1100 10 Tb427.10.11620 TB13 1080 4 Q581T0
TBG5 1100 10 D0A4V8 TBL13 1080 4 Tb427.04.1510
TC5p 1060 37-P Q4DPA3 TBG13 1080 4 C9ZM06
TC13s 1143 34-S Q4DSF6
TB6 Absent
TBL6 Absent TB14 1569 11 Q382N5
TBG6 Absent TBL14 1569 11 Tb427tmp.52.0018
TC6p Absent TBG14 1569 11 D0A9H6
TC14p 1356 (p) 41-P Q4D911
P2D, Na+ transport
TB7 1041 9 Q38CW7 TB15 1128 11 Q386H6
TBL7 1041 9 Tb427tmp.244.2570 TBL15 1128 11 Tb427tmp.02.0850
TBG7 1041 9 C9ZZN4 TBG15 1128 11 D0A6F9
TC7s/7p 1039 39-3, 39-p Q4DST4, Q4DU38 TC15s/15p 1099 14-S, 14-P Q4D434, Q4DGD2
P5A, unknown ion specificity
TB16 1261 8 Q57YG5
TBL16 1261 8 Tb427.08.650
TBG16 1261 8 C9ZUI4
TC16p 1246 19-P Q4DK98

Notes. TB, Trypanosoma brucei brucei (TREU927 strain 927/4 GUTat10.1); TBL, Trypanosoma brucei brucei (strain Lister 427); TBG Trypanosoma brucei gambiense (DAL972, strain MHOM/CI/86/DAL972); TC, Trypanosoma cruzi (strain CL Brener); T. cruzi chromosome designation “S”, Esmeraldo like; T. cruzi chromosome designation “P”, Non-Esmeraldo-like; (p), partial open reading frame. Accession numbers are from the UniProtKB (http://www.uniprot.org/) and TriTrypDB (http://tritrypdb.org/tritrypdb/) databases.